Application

Image

 

 

For over a decade we have built and supported advanced, innovative modular systems to suit our customers' evolving needs. Systems can be integrated into benchtop format for installation on existing laboratory furniture, or designed to be housed in the Smartcel 2 automation workcell.  A few examples of commonly requested Drug Discovery integrations are below. For successful laboratory automation across the UK and EU, Flexible Lab Solutions can help you to automate your processes and advance your laboratory capability. Whatever your application and integration goals, we'd love to hear from you. Contact us today.

Some of our work

A little-known fact: If you are an action movie fan, you may well have spotted our innovative systems used to create futuristic laboratories in blockbuster films such as 'World War Z' and Marvel Studios 'Avengers Assemble' or the SKY sci-fi drama series 'A Discovery of Witches.'

Automated Assay

Automated assay systems contain a wide range of instruments to provide exceptional flexibility. Often designed with a multimode reader like a PHERAstar®, these systems may also have an additional high content imager for expanded capabilities. If speed is a concern, systems can be augmented with multiple pooled devices to reduce bottlenecks.

Intelligent processing can be used to optimise efficiency. For example, a system can be configured to collect data from a multimode plate reader, automatically analyse the data, and then use the results to control how specific plates or wells will be processed further. This type of automatic and rapid feedback is used to further optimise the speed and efficiency of your experiments.

Automated Assay Systems can include a wide range of additional devices such as incubators, compound storage carousels, centrifuges, reagent dispensers, pipettors, acoustic dispensers, plate sealers, plate peelers, plate washers, and more.

Analytical Chemistry

Analytical chemistry systems are used by CDMO’s for Quality Control purposes to test drug production or to automatically run any number of studies necessary for drug development or production. 

Systems usually contain a liquid handler used to adjust protein levels and create a number of test plates for analysis.  An automated spectrophotometer, like the Lunatic from Unchained Labs, can be employed at initiation to sample protein levels and send dilution information to the liquid handling system.  Systems also often contain UPLCs/HPLCs and other analytical testing equipment like the Maurice from Protein Simple for CE-Page or icIEF analysis. 

Analytical chemistry equipment is frequently not designed for automation. Built into the core of Director scheduling software, is a complex I/O control system enabling our engineering team to solve challenges by developing custom automated control systems to replicate the physical actions otherwise performed by a technician.

Vial Management

LabworX™ systems can handle microplates, flasks, microtubes, or vials. Our vial management systems manipulate individual vials or racks of vials. These systems can add barcodes to individual vials or racks, tare and weigh vials, and remove or add material to each vial. Often used by chemistry departments to manage chemicals or by Quality Control departments testing products, they are designed with robust 24/7 operation in mind.

High Content Screening

HCS system designs can be as simple as combining a room temperature hotel with any standard imager to enable overnight operation of fixed samples. More complex systems may contain pipettors, cell dispensers, plate washers, and incubators enabling complex staining procedures followed by automated imaging. Whether you’re running a simple fixed assay, a multiweek Cell Painting campaign, or imaging live organoids, our HCS systems will provide simple and robust 24/7 operations.

Application Application Application Application Application Application